GenomePlex C-WGA for fixed and other degraded DNA
Reproducible Whole Genome Amplification from Fixed and Other Degraded Samples
GenomePlex C-WGA applications:
* Test for mutations, SNPs, CNVs, and aneuploidies from biopsies and surgical tissue
* Biomarker discovery from archived FFPE sections
* Genomic profiling of fixed FACS samples
GenomePlex™ C-WGA is based on special enzymes and random-priming oligonucleotides to make and amplify a library of short, overlapping amplimers that are a very faithful representation of genomic DNA. Unlike other technologies, GenomePlex yields excellent results with fragmented DNA greater than 400 b long even if containing lesions. It is a very effective method to amplify DNA damaged from formalin fixation, radiation, or shearing. GenomePlex is not recommended for less than 100 analyte copies because of reduced reproducibility.
GenomePlex Workflow
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