Talk to a Scientist
Rubicon Genomics is committed to knowledge sharing and the stimulating discussion of ideas. October 2012 saw Rubicon launch a series of educational webinars supporting this objective. Each of these presentations is currently available via recording with brief descriptions and links to the recordings provided below. As the list of offering expands, please visit our News section for a full listing.
Rubicon welcomes discussion and inquiry; please contact us with any questions or suggestions.
“Advancing Gold Standard for Single-Cell Aneuploidy, CNV and Mutations into the Next-Gen Era,” May 1, 2013.
PicoPLEX-WGA has become the gold standard for diagnostic aneuploidy and mutation testing of single human sperm, polar bodies, and blastomeres, and is now deployed worldwide in 90% of IVF genetic testing. Rubicon is developing PicoPLEX-scD, which is designed to make single-cell NGS libraries for the Illumina and LifeTechnologies platforms.
Topics:
- Tools available for single-cell genomic DNA analysis
- Challenges for single cell testing
- Genetic analytes for single-cell preimplantation, prenatal, and cancer testing
- The clinical record of PicoPLEX WGA in detection of aneuploidy and single-gene disorders in IVF cases
- Preliminary NGS results using PicoPLEX-scD for single cell genetic studies.
Audience members will gain a better understanding of the rapidly changing challenges and solutions to single-cell genetics.
Presented by Dr. John P. Langmore, Co-Founder and Chief Scientific Officer, Rubicon Genomics
"What's Next in Next-Generation Sequencing?" Hosted by The Scientist and sponsored by Rubicon, March 5, 2013.
The advent of next-generation sequencing is considered the most disruptive technological advance, as it has resulted in the doubling of sequence data almost every 5 months and the precipitous drop in the cost of sequencing a DNA base. The first webinar to be conducted in March will track the evolution of next-generation sequencing (NGS) and what the future holds in terms of the technology and its applications. Following brief presentations given by our panel of experts, there will be a live Q&A session where attendees can ask questions and discuss NGS-related challenges they are facing in their laboratories.
Topics:
• How NGS has evolved over the years
• Current limitations with the technology
• Challenges with data storage and analysis
• What the future holds for NGS
Speaker Schedule:
The Future of NGS for Open Access Genome and Trait Data
- Dr. George Church, Professor, Department of Genetics, Harvard Medical School
Next-Generation Microbiology and Infectious Disease Research
- Dr. George Weinstock, Professor of Genetics and Molecular Microbiology, Washington University
The Future of NGS for Systems Medicine and Multiscale Biology
- Dr. Joel Dudley, Assistant Professor of Genetics and Genomic Sciences and Director of Biomedical Informatics, Mount Sinai School of Medicine
"Challenges and Solutions for Sequencing Clinical Samples" October 30, 2012.
NGS has dramatically reduced the time and cost of sequencing DNA, creating an explosion of new research and clinical applications that depend on sequencing. In spite of this success, clinical samples such as FFPE, plasma, and single cell DNA are difficult to prepare for NGS. This webinar presentation will explain why these samples are challenging, identify the shortcomings of the first-generation NGS preps, and discuss how new technologies are removing the NGS sample preparation barrier.
Presented by Dr. John P. Langmore, Co-Founder and Chief Scientific Officer, Rubicon Genomics