Rubicon Genomics Sponsored Webinar Recording Available: "What's Next in Next-Generation Sequencing?"
Presented by THE SCIENTIST
Original broadcast date: March 5, 2013, 2:30 - 4:00 pm ET
The advent of next-generation sequencing is considered the most disruptive technological advance, as it has resulted in the doubling of sequence data almost every 5 months and the precipitous drop in the cost of sequencing a DNA base. The first webinar to be conducted in March will track the evolution of next-generation sequencing (NGS) and what the future holds in terms of the technology and its applications. Following brief presentations given by our panel of experts, there will be a live Q&A session where attendees can ask questions and discuss NGS-related challenges they are facing in their laboratories.
• How NGS has evolved over the years
• Current limitations with the technology
• Challenges with data storage and analysis
• What the future holds for NGS
The Future of NGS for Open Access Genome and Trait Data
Dr. George Church, Professor, Department of Genetics, Harvard Medical School
60 years after the first 3D DNA structure we might soon see the first complete human genome and first true 3D structure of a genome. In order to gain value from this we need open-access data on millions of human genome, environment and trait data (Personalgenomes.org).
Next-Generation Microbiology and Infectious Disease Research
Dr. George Weinstock, Professor of Genetics and Molecular Microbiology, Washington University
The new world of microbial research tackles problems by sequencing hundreds of isolated microbes, or hundreds of dense microbial communities. These data sets allow in-depth studies with ecological, population genetic, and other approaches being more prominent in analyses. The time when the combination of these disciplines is routine is not far off, resulting in new dimensions to understanding microbial phenomena with consequent new applications.
The Future of NGS for Systems Medicine and Multiscale Biology
Dr. Joel Dudley, Assistant Professor of Genetics and Genomic Sciences and Director of Biomedical Informatics, Mount Sinai School of Medicine
60 years after gaining the first glimpse of the structure of the DNA molecule, we can now elucidate the structure of multiscale networks that connect DNA variation to the activities and functions of entire systems of RNAs, proteins, metabolites, cells, tissues, organ systems, microbial communities, and external environmental influences as they operate in the context of complex living systems. Real-time DNA sequencing technologies and multiscale network modeling will vastly broaden our understanding of human disease and its drivers, and enable more precise and predictive models of individual health.