PlasmaPlex™ WGA for Plasma, Serum, Urine
Reproducible Whole Genome Amplification from small amounts of apoptotic DNA
PlasmaPlex™ WGA makes full use of short double-stranded DNA molecules, giving you:
- Reliable testing of plasma, serum, urine and other clinical samples
- Selective amplification of circulating tumor and fetal cell DNA fragments
- The ability to complete epidemiological and pharmacogenomic studies from archived plasma or serum
- Higher sensitivity for non-invasive diagnostic, prognostic, and predictive tests
Superior Performance
- Highly representative amplification of entire human or other genomes
- Effective for double-stranded DNA between 100 – 2,000 bp in length
- > 90% genotyping success rate from archived serum or plasma
- >10X more efficient than the most popular method for plasma WGA
- Faithful representation even for GC-rich sequences
Simple, Rapid Protocol
- Single-tube, 3-hour, 2-step process
- No intermediate purifications, no final purification necessary
- Completely automatable
Important Features of PlasmaPlex Amplified DNA
- High sequence fidelity
- Molecular weight same as template DNA
- Virtually no primer dimers, chimeras, or extraneous DNA background
- Validated for Q-PCR, oligonucleotide aCGH, genotyping, mutation detection, sequencing, and methylation analysis
- Used in testing of over 10,000 clinical plasma/serum samples
The PlasmaPlex WGA kits amplify 50 samples for microarray, Q-PCR or NGS analysis. For research use only. Any commercial use requires separate Rubicon license.
The PlasmaPlex WGA Kit is in development. For early access, please contact Rubicon.